前额叶皮质在调节人类和动物的侵略性方面的作用
Xinyang Li1, Lize Xiong2, Yan Li3
1Department of Psychiatry and Center for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence and Department of Anesthesiology and Perioperative Medicine, Shanghai Fourth People's Hospital Affiliated with Tongji University School of Medicine, Shanghai, China.
Behavioural brain research
|October 6, 2024
概括
前额叶皮层 (PFC) 通过神经和分子通路调节侵略性. 本综述综合了人类和动物的PFC攻击联系,探索了分子,电路和疾病层面的联系.
科学领域:
- 神经科学是一个神经科学.
- 行为科学 行为科学
背景情况:
- 前额叶皮层 (PFC) 参与了侵略,但潜在的机制尚未完全理解.
- 现有的关于PFC在侵略中的作用的研究存在不一致性,需要进一步探索.
研究的目的:
- 巩固当前关于前额叶皮层与侵略之间的关系的知识.
- 阐明神经机制和分子途径参与PFC介导的侵略调节.
主要方法:
- 关于PFC解剖学,功能和侵略性的人类和动物研究的综述.
- 对分子神经调节剂,皮层下投影和与PFC功能相关的精神疾病的分析.
主要成果:
- 通过分子通路和皮层下电路,PFC会影响侵略性.
- 在某些人类精神疾病中,PFC变化与增加的侵略性相关.
结论:
- 本综述为理解PFC对侵略的调制提供了一个框架.
- 识别了先前发现的悖论,并建议了未来的研究方向.
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