前极皮质在调整人类类动物响应执行和行动抑制之间的平衡中的作用
Azadeh Feizpour1, Mark J Buckley2, Inaki C Mundinano1
1Cognitive Neuroscience Laboratory, Department of Physiology and Neuroscience Program, Biomedicine Discovery Institute, Monash University, Victoria 3800, Australia.
前极皮质对于控制反应执行至关重要,而不是抑制行动. 对这个大脑区域的损伤会损害与实践和背景相关的行为调整,影响反应时间.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 灵长类动物的行为
背景情况:
- 执行控制包括平衡响应执行和行动抑制.
- 在人类类动物中突出的前极皮质在这种平衡中扮演着未被研究的角色.
研究的目的:
- 调查前极皮质在调节动作执行和抑制方面的作用.
- 为了比较人类和在停止信号任务上的表现,并评估损伤效应.
主要方法:
- 在人类和子子中使用停止信号任务进行跨物种研究.
- 在子选择性双边前极地皮层病变之前和之后评估行为调整.
主要成果:
- 这两种物种都表现出与实践相关的和取决于背景的行为调整.
- 面极损伤的子表现出更长的反应时间和改变了与实践相关的调整.
- 前极损伤没有影响抑制能力,但改变了错误后和停止后的调整.
结论:
- 前极皮质对于分配控制到响应执行至关重要.
- 这一大脑区域似乎并不必不可少,以抑制行动.
- 这些发现强调了前极皮质在灵活的行为控制中的作用.
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