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Updated: Jun 11, 2025

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AP-2α通过降低MGMT表达和改善DNA损伤来降低复发性GBM的TMZ抵抗力

Guixiang Huang1, Mi Ouyang1, Kai Xiao2

  • 1The National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Science, Hunan Normal University, Changsha 410081, China; State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Science, Hunan Normal University, Changsha 410081, China.

Life sciences
|October 6, 2024
PubMed
概括

激活转录因子AP-2α通过降低MGMT的调节来抑制质瘤复发. 视网素酸 (RA) 增强AP-2α,为治疗复发性质瘤提供了一种新的策略.

关键词:
AP-2α 是一个AP-2α.造成的DNA损伤是DNA损伤.质瘤的复发情况在MGMT中,我们可以看到MGMT.

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