在糖尿病前的吸烟者和非吸烟者中口服酵母的运输
1Department of Oral Maxillofacial Surgery and Diagnostic Sciences, College of Medicine and Dentistry, Riyadh Elm University, Riyadh, Saudi Arabia.
International dental journal
|October 6, 2024
概括
糖尿病前期和吸烟显著增加了口腔酵母携带 (OYC). 高血糖症在糖尿病前吸烟者中驱动OYC,而牙周炎症在非糖尿病吸烟者中是关键因素.
科学领域:
- 口腔微生物学 口腔微生物学
- 公共卫生 公共卫生
- 内分泌学 在内分泌学.
背景情况:
- 习惯性吸烟和糖尿病前期是增加口腔酵母携带 (OYC) 的独立危险因素.
- 没有先前的研究比较了OYC在香烟吸烟者和非吸烟者,并没有糖尿病前期.
- 这项研究旨在解决这一研究缺口.
研究的目的:
- 为了比较口服酵母携带 (OYC) 在四组:糖尿病前吸烟者,非糖尿病前吸烟者,糖尿病前不吸烟者和非糖尿病前不吸烟者.
- 调查糖尿病前期和吸烟对OYC的影响.
- 在不同参与者群体中确定决定OYC的因素.
主要方法:
- 92名参与者根据吸烟状况和糖尿病前期 (HbA1c 5.7%-6.4%) 被分为四组.
- 收集的数据包括人口统计,HbA1c,吸烟史 (包装年),口腔卫生和牙科史.
- 口服酵母携带 (OYC) 通过口服冲洗取样,以及牙周检查和非刺激全唾液流量 (UWSFR) 测定来评估.
主要成果:
- 口服酵母携带 (OYC) 在糖尿病前吸烟者中明显高于所有其他组.
- 无论是糖尿病前期吸烟者还是非糖尿病前期吸烟者,OYC都比非吸烟者高.
- 与健康的非吸烟者相比,吸烟者和糖尿病前的非吸烟者中牙周参数 (斑块指数,附着损失,探测深度,缺失的牙) 更差.
结论:
- 在糖尿病前期吸烟者中,OYC受高血糖的影响.
- 在非糖尿病吸烟者中,牙周炎症的严重程度是OYC的主要决定因素.
- 吸烟和糖尿病前期都会增加口腔酵母的携带,有着不同的潜在机制.
相关概念视频
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:22Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
01:22Chronic Obstructive Pulmonary Disease
1.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.2K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.7K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.7K
01:20COPD: Pathogenesis and Clinical Features
242
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
242
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K