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Updated: Jun 11, 2025

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Microfluidics in Assessing Platelet Function
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在患有血栓缩症的患者中,经过dentoalveolar手术后的术后出血 - - 预防性血小板输血是否必要?
Johan Lundström1,2, Samuel Wiqvist3, Martin Jädersten4,5
1Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden. johan.n.lundstrom@regionstockholm.se.
概括
预防性血小板输血并不能显著减少手术后出血后dentoalveolar手术在患有低血小板计数的患者. 然而,一次切除多颗牙会增加出血的风险.
科学领域:
- 口腔和牙面部外科手术
- 血液学 血液学 血液学
背景情况:
- 牙气囊外科手术带有术后出血 (POB) 的风险.
- 预防性血小板 (PLT) 输血在接受此类手术的血小板缺血 (PLT 数 ≤ 75*10^9/L) 患者的疗效尚不清楚.
研究的目的:
- 调查预防性PLT输血对POB发病率的影响.
- 为了评估经过牙气管外科手术的血小板缺血患者的POB率.
主要方法:
- 在83名患者的回顾性研究中,PLT计数≤75*10^9/L的患者接受了牙气囊手术.
- 在接受预防性PLT输血的患者和没有接受PLT输血的患者之间比较POB事件.
- 排除患有其他凝血缺陷或混药物的患者.
主要成果:
- 在所有患者中,POB发生在6.0% (中位数PLT数量为35*10^9/L).
- 4.2%的输血患者 (n=48) 和8.6%的非输血患者 (n=35) 经历了POB (p=0.646).
- 当两个或两个以上的牙同时被切除时,观察到明显更高的POB发生率 (p=0.042).
结论:
- 预防性PLT输血似乎不能减少POB发病率在经历牙脉外科手术的血栓缺血患者.
- 由于POB风险增加,建议在一次会议中进行多次拔牙时谨慎行事.
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