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Updated: Jun 11, 2025

High-Throughput Cardiotoxicity Screening Using Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Monolayers
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环境线索促进人类诱导的多能干干细胞衍生的心肌细胞的成熟和模式

Enrique Coca1, Scott Cho1, Christopher Kauffman1

  • 1Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, USA.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
|October 7, 2024
PubMed
概括

使用脱细胞化心脏细胞外矩阵 (ECM) 促进诱导多能干细胞衍生心肌细胞 (iPSC-CMs) 的成熟和组织. 这种生物材料基质增强了用于心血管研究的iPSC-CM开发.

关键词:
人类诱导的多能干细胞; 心肌细胞; 细胞外基质; 成熟.

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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