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相关概念视频

Cancer Prevention02:59

Cancer Prevention

6.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
333
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
8.7K
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
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Oogenesis02:07

Oogenesis

63.5K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.5K
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

7.3K
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
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相关实验视频

Updated: Jun 11, 2025

In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose
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In Vivo and Ex Vivo Approaches to Study Ovarian Cancer Metastatic Colonization of Milky Spot Structures in Peritoneal Adipose

Published on: October 14, 2015

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对妇科癌症的遗传倾向

Tavia González Peña1, Marilyn Huang2

  • 1Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee.

Clinical obstetrics and gynecology
|October 7, 2024
PubMed
概括

初级保健提供者可以通过家庭病史评估和遗传检测来识别遗传性癌症综合征 (HCS). 早期检测可以为妇科癌症提供个性化的预防策略.

科学领域:

  • 在瘤学瘤学.
  • 遗传学 遗传学 是一个
  • 预防医学 预防医学

背景情况:

  • 遗传性癌症综合征 (HCS) 占所有癌症的10%.
  • 目前的癌症敏感性测试通常发生在诊断后.
  • 初级保健提供者在早期HCS识别中发挥着关键作用.

研究的目的:

  • 审查常见的妇科遗传癌症综合征的方法和评估.
  • 突出初级保健提供者在遗传性癌症风险评估中的机会.
  • 强调早期遗传检测和风险识别的好处.

主要方法:

  • 关于常见的妇科遗传癌症综合征的文献综述.
  • 评估家族史评估协议的评估.
  • 对基因测试启动策略的评估.

主要成果:

  • 识别患有HCS的个体可以进行初级预防.
  • 可以实施增强查和个性化护理策略.
  • 妇产科医生可以在风险评估中发挥至关重要的作用.

结论:

  • 将遗传性癌症风险评估纳入初级保健是必不可少的.

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  • 通过基因检测早期识别HCS可以改善患者的治疗结果.
  • 妇科HCS的积极管理可以减少癌症发病率和死亡率.