在双边切除术后的偶发性细胞癌,发生在自身主导的多囊性病中
1Division of General Surgery, Department of Hepato-Bilio-Pancreatic Surgery and Transplantation Surgery, Chosun University College of Medicine, Gwangju 61453, South Korea.
World journal of clinical cases
|October 7, 2024
概括
自体主导性多囊性病 (ADPKD) 的透析患者患细胞癌 (RCC) 的患病率更高. 通过监测计划进行早期检测对于管理这些个体的RCC至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 自体主导多囊性病 (ADPKD) 与细胞癌 (RCC) 的发病率高于一般人群.
- 在ADPKD患者中诊断RCC是复杂的,因为有很多囊,往往会延迟识别并误诊为感染或出血.
研究的目的:
- 确定细胞癌 (RCC) 的患病率和临床特征在患有自身主导性多囊性病 (ADPKD) 的患者中.
- 分析ADPKD患者的结局,这些患者因末期病 (ESRD) 接受了同时进行双边本源切除术.
主要方法:
- 一组19名在血液透析等待移植的ADPKD患者在2017年5月至2024年4月期间接受了双边本地切除术.
- 收集的数据包括患者人口统计,手术细节 (输血,输血,手术时间),住院时间和术后并发症.
- 对切除的脏的病理发现进行了审查,以确定RCC的存在和特征.
主要成果:
- 细胞癌 (RCC) 检测到21.1%的患者 (15.8%的脏),其中两名患者患有多焦点性疾病.
- 所有确定的RCC都是pT1阶段,平均最大的病变直径为16.5毫米.
- 平均手术持续时间为120分钟,平均血液损失为184.2毫升; 5名患者需要输血,5名患者经历了术后并发症.
结论:
- 细胞癌 (RCC) 的患病率在患有末期脏病 (ESRD) 的自身主导多囊性脏病 (ADPKD) 患者中较高.
- 临床医生应保持高的怀疑指数,并实施对ADPKD患者的RCC监测协议,特别是那些接受透析的患者.
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