一项为期三年的纵向随访研究:轻度认知障碍是否加速与年龄相关的身体功能和身体成分变化?
Hyuma Makizako1, Shoma Akaida2, Mana Tateishi3
1Department of Physical Therapy, Kagoshima University, Kagoshima, JPN.
Cureus
|October 7, 2024
概括
轻度认知障碍 (MCI) 显著影响老年女性的身体组成,加速BMI和肌肉质量下降. 这凸显了针对患有MCI的妇女进行有针对性的干预的必要性,以应对这些与年龄相关的变化.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 人体生理学 人体生理学
背景情况:
- 与年龄相关的认知能力下降,包括轻度认知障碍 (MCI),通常与身体功能和身体组成的变化有关.
- 了解认知状态和身体衰老之间的相互作用对于开发有效的老年干预措施至关重要.
研究的目的:
- 研究轻度认知障碍 (MCI) 对社区老年人的身体功能和身体组成的纵向影响.
- 确定MCI是否影响与年龄相关的握力,步行速度,体重指数 (BMI) 和尾骨肌指数 (ASMI) 的变化.
主要方法:
- 一项涉及180名老年人 (≥70岁) 的前性研究,进行了基线和三年后续评估.
- 通过使用标准化认知测试来诊断轻度认知障碍 (MCI).
- 在基线和随访时测量身体功能和身体成分 (BMI,ASMI).
- 双向重复测量 ANCOVA 用于根据时间相互作用分析组 (MCI与非MCI),根据年龄和性别进行调整.
主要成果:
- 对于整体身体功能或身体组成,没有发现显著的分组时间相互作用.
- 然而,按性别分层分析显示,女性BMI和ASMI的群体对时间的显著相互作用.
- 与没有MCI的女性相比,患有MCI的老年女性的BMI和ASMI下降幅度更大.
结论:
- 轻度认知障碍 (MCI) 可能加速与年龄相关的体重和肌肉质量下降,特别是在老年女性中.
- 这些发现强调了在解决身体衰老和身体组成变化时考虑女性认知状态的重要性.
- 对患有MCI的女性进行有针对性的干预可以减轻对肌肉质量和整体体质的不良影响.
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