血清雌激醇水平与绝经后妇女腹腔大动脉化之间的关联:一个横截面研究
1Division of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Frontiers in endocrinology
|October 7, 2024
概括
较低的雌激素 (E2) 水平与绝经后妇女腹腔大动脉化 (AAC) 风险增加有关. 监测E2可能有助于预防心血管疾病.
科学领域:
- 内分泌学 在内分泌学.
- 心血管健康 心血管健康
- 老年学是一门学科.
背景情况:
- 在绝经后的女性中,雌激醇 (E2) 和腹腔大动脉化 (AAC) 之间的关系尚不清楚.
- 绝经后的女性经历激素变化,这可能会影响心血管健康.
研究的目的:
- 调查血清雌激醇水平与绝经后妇女腹腔大动脉化的流行之间的关联.
- 为了确定较低的E2水平是否与发展AAC的更高风险相关.
主要方法:
- 从2013-2014年NHANES调查中分析了614名绝经后妇女的数据.
- 根据血清E2水平将参与者分类为三角动物.
- 用于评估E2水平与已确定的EAAC (符合条件的腹腔大动脉化) 患病率之间的关联的后勤回归模型.
主要成果:
- 与中间 (9.8%) 和最高 (8.3%) 的第三层相比,EAAC的流行率在最低的E2第三层 (16.6%) 中显著更高.
- 降低E2水平与EAAC的风险增加有关.
- 最低E2三位数的女性患EAAC的风险是最高三位数的2.55倍,与最高三位数相比.
结论:
- 绝经后妇女中AAC的更高患病率与血清E2水平较低有关.
- 雌激醇在维持绝经后妇女的心血管健康方面发挥着至关重要的作用.
- 监测E2水平可能有助于早期预防和管理AAC和相关心血管疾病.
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