RNA动力学会影响白血病细胞系对转录干扰的反应

Izabela Todorovski1,2, Mary-Jane Tsang1,2, Breon Feran3,4

  • 1Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.

NAR cancer
|October 7, 2024
PubMed
概括

mRNA衰变速率,而不仅仅是产量,决定了癌症药物选择性. 快速衰变的基因对转录抑制剂更敏感. 调节mRNA周转为白血病提供了新的治疗策略.

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