相关实验视频
Updated: Jun 11, 2025

07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
307
在老年人中肺栓塞的管理和结果
Eishan Beotra1, Vincent J J Ngian1,2,3, Fiona Tran1,2,3
1South Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.
International journal of general medicine
|October 7, 2024
概括
直接口服抗凝剂 (DOAC) 在所有年龄组的肺栓塞 (PE) 治疗中显示出类似的安全性和有效性. 这项研究表明,目前在老年人群中治疗PE的治疗方案不需要改变.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 药理学 药理学是指药理学的学科.
背景情况:
- 肺栓塞 (PE) 治疗随着直接口服抗凝剂 (DOAC) 的引入而发展.
- 在老年人 (≥85岁) 中,PE的发病率正在上升,但对其管理和结果的研究是有限的.
研究的目的:
- 将85岁及以上患者的肺栓塞 (PE) 管理和临床结果与其他年龄组患者进行比较.
- 评估老年PE患者不同抗凝策略的有效性和安全性.
主要方法:
- 一项回顾性队列研究,涉及373名通过CTPA或VQ扫描确认肺栓塞 (PE) 的患者.
- 数据收集包括人口统计,并发症 (查尔森指数),治疗类型和结果 (并发症,复发,死亡率).
主要成果:
- 直接口服抗凝剂 (DOACs) 被处方给53.4%的患者.
- 在最年长的组 (≥85岁),LMWH与华法林之间的桥梁是最常见的治疗方法 (46.2%).
- 在所有年龄组中,主要出血事件很少发生 (1.7%),没有观察到显著的结果差异.
结论:
- 对于肺栓塞 (PE) 治疗的DOAC的安全性和有效性在不同年龄组中似乎是一致的.
- 这些发现支持目前在老年人群中治疗PE的治疗方案,尽管需要进一步的研究.
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