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Updated: Jul 20, 2026

Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach
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儿童麻醉和自闭症风险:人口和小鼠研究

Mingyang Sun1, Ningning Fu1, Ting Li1

  • 1Department of Anesthesiology and Perioperative Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Henan University People's Hospital, Zhengzhou, Henan 450003, China.

Brain communications
|October 7, 2024
PubMed
概括

儿童早期接触全身麻醉与患自闭症谱系障碍的风险更高有关. 鼠标研究表明,sevoflurane麻醉诱导了类似自闭症的行为,并改变了与自闭症相关的基因表达.

关键词:
麻醉 anesthesia 这是一种麻醉.自闭症自闭症是什么童年的童年 童年的童年队列研究是一项队列研究.鼠类模型模型

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Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...