短睡眠时间和阻塞性睡眠呼吸暂停与中心肥胖症的关联:使用人体测量措施的回顾性研究
Yi Li1,2,3, Yixuan Lu1,2, Youdan Zhao1
1Department of Senior Cadres Ward, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, People's Republic of China.
Nature and science of sleep
|October 7, 2024
概括
体重指数 (BMI) 和腰高比 (WHtR) 可以帮助识别与阻塞性睡眠呼吸暂停 (OSA) 和睡眠时间短暂相关的中心肥胖症. 这些简单的措施可以作为临床环境中的可访问指标.
科学领域:
- 医学科学 医学科学 医学科学
- 肥胖问题研究研究
- 睡眠医学 睡眠医学
背景情况:
- 中心肥胖与阻塞性睡眠呼吸暂停 (OSA) 和睡眠时间短暂有关.
- 对内脏肥胖的客观测量 (CT,MRI,DXA) 是昂贵且难以获得的.
- 需要可访问的人类测量措施作为内脏脂肪的替代品.
研究的目的:
- 评估身体质量指数 (BMI) 和腰高比 (WHtR) 作为OSA和睡眠时间短暂的内脏肥胖的替代指标.
- 评估WHtR和BMI在评估内脏肥胖的综合实用性.
主要方法:
- 对333名成年人进行了回顾性分析,记录了多睡眠学 (PSG) 记录.
- 逻辑回归用于评估BMI,WHtR,OSA和睡眠时间短暂之间的关联.
- 接收器运行特征 (ROC) 曲线分析以评估预测能力.
主要成果:
- 综合WHtR和BMI显著与OSA和睡眠时间短暂相关 (p<0.05).
- 睡眠延迟和睡眠开始后醒来独立预测了睡眠不足的OSA患者的中心肥胖风险.
- 结合BMI和WHtR,与单个措施相比,可以更好地评估中心脂肪.
结论:
- 体重指数和WHtR显示与OSA和睡眠时间短暂有显著的关联,作为中心肥胖症的潜在替代标志物.
- 睡眠参数,如潜伏时间和睡眠开始后的觉醒,可以预测中心肥胖风险.
- 需要进一步的前性研究来验证这些发现.
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