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通过蛋白质性CSF剖析来定义阿尔茨海默病

Carmen Peña-Bautista1, Lourdes Álvarez-Sánchez1, Ángel Balaguer2

  • 1Alzheimer's Disease Research Group, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.

Journal of proteome research
|October 7, 2024
PubMed
概括

阿尔茨海默病 (AD) 涉及复杂的途径. 脑脊液的蛋白质组分析揭示了不同的蛋白质配置,并确定了因AD而出现的轻度认知障碍的两种亚型,突出显示了疾病的异质性.

关键词:
在CSF的CSF中,阿尔茨海默病是什么意思 阿尔茨海默病是什么意思路径 路径 路径蛋白质组学 蛋白质组学小型类型 亚型 类型

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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