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Updated: Jun 11, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Published on: February 20, 2018

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在人类和动物大麻素CB1受体中没有证据表明内分类固醇诱导的G蛋白亚型选择性

Xiaoxi Zheng1, Beth Ehrlich1, David Finlay1

  • 1Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.

Cannabis and cannabinoid research
|October 7, 2024
PubMed
概括

阿拉基多乙醇胺 (AEA) 和2-阿拉基多乙醇 (2-AG) 在大麻素CB1受体上没有显示G蛋白亚型选择性. 这种缺乏选择性在人类变体和物种中是一致的,包括动物受体.

关键词:
选择性G蛋白亚型的选择性它们是TRUPATH生物传感器.大麻素受体的受体是什么这是一种内分泌大麻素 (endocannabinoid).对偏差的操作分析.

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