通过结合茎衍生的激剂激活聚素-1信号传递

Shristi Pawnikar1, Brenda S Magenheimer2,3, Keya Joshi4

  • 1Center for Computational Biology and Department of Molecular Biosciences, University of Kansas, Lawrence, United States.

eLife
|October 7, 2024
PubMed
概括

针对Polycystin-1 (PC1) 茎的合成片重新激活了蛋白质的突变形式的信号传递. 这项研究揭示了PC1激活的结构动态,有助于开发新的自身主导多性病 (ADPKD) 疗法.

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