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亚托皮肤炎与儿童线性生长之间的关联-一个系统性审查

Gheslynn Gerard¹, Wen Wei Victoria Ng¹, Jin Kai Jonathan Koh¹

¹Ministry of Health Holdings, Singapore, Singapore.

European journal of pediatrics

|October 7, 2024

概括

儿童类皮肤炎 (AD) 和线性生长障碍之间的联系是微弱和不一致的. 然而,严重的AD,早期发病,睡眠不足和饮食限制可能会增加生长问题的风险.

科学领域:

儿科皮肤病学儿科皮肤病学
增长和发展增长和发展
系统审查是系统的审查.

背景情况:

关于亚托皮性皮肤炎 (AD) 与儿童线性生长之间的关联,存在不一致的证据.
一些研究表明,阿尔茨海默病对身高有负面影响,而另一些研究则报告没有显著的关联.

研究的目的:

评估儿童类皮肤炎 (AD) 与线性生长之间的关联.
确定导致AD儿童线性生长受损的因素.

主要方法:

进行了符合PRISMA的系统审查.
搜索了PubMed,Embase,Scopus和Cochrane数据库,从创立到2024年6月.
包括14项研究 (50,146名患者),并使用Joanna Briggs Institute和GRADE标准评估研究质量.

主要成果:

七项研究报告说,阿尔茨海默病与低身高标准偏差分数 (SDS) 之间存在正相关性;其他研究发现没有相关性.
只有3项研究的证据质量中等,所有研究都表明阿尔茨海默病患者的身高SDS较差.
严重的AD,早期发病,睡眠障碍和食物限制是线性生长障碍的危险因素;局部类固醇使用不是.

结论:

目前的证据表明,儿童阿尔茨海默病与线性生长不良之间的联系是微弱和不一致的.
线性生长的短暂减缓可能会发生,模仿宪法延迟.
患有严重阿尔茨海默病,早期发病,睡眠不足和营养限制的儿童更容易患上生长障碍.

关键词:

亚托邦性皮肤炎 (Atopic Dermatitis) 是一种不良的疾病.湿疹湿疹是一种湿疹高度身高高度高度高度线性增长是一种线性增长.矮身的身材低矮的人.

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