丹麦居民的COVID-19后状态疲劳结果
Elisabeth O'Regan1, Lampros Spiliopoulos1, Ingrid Bech Svalgaard1
1Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
JAMA network open
|October 7, 2024
概括
感染COVID-19可能会导致持久的疲劳和劳动后的不适,特别是在住院后. 在接种疫苗的人中,先前存在的精神疾病并没有显著改变这些长期疲劳症状.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 疲劳是COVID-19后病情的一个常见和衰弱的症状.
- 现有的关于COVID-19后疲劳的研究受到人口选择和缺乏非感染对照的限制.
- 感染严重程度和精神疾病对COVID-19后疲劳的影响尚不清楚.
研究的目的:
- 评估SARS-CoV-2感染对自我报告的疲劳和后劳动不适的长期影响.
- 调查COVID-19后疲劳的危险因素,包括住院和先前存在的精神疾病.
主要方法:
- 参与EFTER-COVID调查的15岁以上丹麦居民的队列研究.
- 通过反复的,自我报告的在线问卷,收集了关于疲劳和劳动后不适的数据.
- 混合效应模型比较了SARS-CoV-2测试阳性和测试阴性个体之间的结果,测试后2至18个月.
主要成果:
- 感染SARS-CoV-2与疲劳得分增加3%有关,并使后劳动不适的几率增加了一倍.
- 由于SARS-CoV-2的住院治疗显著增加了23%的疲劳得分.
- 之前存在的精神疾病并没有显著改变COVID-19后的疲劳症状.
结论:
- 轻微的SARS-CoV-2感染与疲劳和后劳动不适的微妙增加有关.
- 严重的急性SARS-CoV-2感染,特别是需要住院治疗,会导致更严重的后急性症状.
- 对疲劳的临床随访对于经历过严重急性SARS-CoV-2感染的个人可能是有益的.
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