通过调节HDAC6,NF-kB促进了侵袭性细胞的形成,反过来又维持了维门丁

Jo-Mei Maureen Chen1,2, Cheng-Yen Chuang3,4, Chiao-Yun Cheng1

  • 1Department of Applied Chemistry, National Chi Nan University, Nantou, Taiwan.

概括

核因子-kappa B (NF-κB) 通过提高HDAC6的调节来控制攻击性形成,该HDAC6维护维门丁. 抑制NF-κB增强了蛋白酶体抑制剂对癌细胞的疗效.

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