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Updated: Jun 20, 2026

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
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条件概率扩散模型驱动的合成放射基因组应用在乳腺癌中

Lianghong Chen1, Zi Huai Huang2, Yan Sun1,2

  • 1Department of Computer Science, Western University, London, Ontario, Canada.

PLoS computational biology
|October 7, 2024
PubMed
概括

这项研究使用了一种新的条件概率扩散模型 (CPDM) 来从基因组数据中创建合成乳腺癌 (BC) MRI. 这些合成图像有助于预测BC亚型和患者存活率,推进精准医学.

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Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase01:11

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...