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Updated: Jun 11, 2025

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
12:02

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols

Published on: June 6, 2017

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修订了基尿素诱导细胞循环停止的机制,并改进了替代的替代方法

Alisa E Shaw1, Mattias N Mihelich1, Jackson E Whitted1

  • 1Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80525.

Proceedings of the National Academy of Sciences of the United States of America
|October 7, 2024
PubMed
概括

氧尿素 (HU) 通过增加活性氧物种 (ROS),抑制DNA聚合酶,导致复制应激. 一个新的工具,RNR-deg,为研究复制检查点提供了一个更安全的替代方案.

关键词:
这就是ROSOS ROS.在S阶段的检查点.细胞循环中的细胞循环.基尿素的含量是多少复制压力是复制的压力.

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