患者报告的代谢功能障碍相关的脂肪性肝病的结果
Aurora Barberá1,2, Trenton M White2, Anish K Arora3
1The Global NASH Council, Washington, District of Columbia.
Seminars in liver disease
|October 7, 2024
概括
与代谢功能障碍相关的脂肪性肝病 (MASLD) 影响全球数百万人,可能会恶化为MASH. 本综述探讨了如何使用患者报告的结果指标 (PROM) 来理解患者的经验,并指导MASLD/MASH护理.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 临床医学 临床医学
- 患者报告的结果
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一种普遍存在的全球性肝病.
- MASLD可以进入严重的阶段,如代谢功能障碍相关的脂肪肝炎 (MASH),肝硬化和肝细胞癌.
- 患MASH的危险因素包括肥胖,2型糖尿病,脂质不良和代谢综合征.
研究的目的:
- 调查患者报告结果措施 (PROMs) 在管理MASLD和MASH时的使用.
- 确定在临床实践中用于这些疾病的特定PROM.
- 总结患者报告的与MASLD和MASH相关的结果.
主要方法:
- 在MASLD/MASH.中对PROM的文献进行系统审查.
- 对使用PROMs进行患者评估的研究进行分析.
- 综合报告的患者结果和生活质量数据.
主要成果:
- 患有MASH的患者经常报告与健康有关的生活质量下降.
- 损伤的主要领域包括身体功能,疲劳和活力.
- PROMs为患者提供了关于症状和治疗有效性的关键观点.
结论:
- 为了全面了解MASLD和MASH患者的体验,PROM是必不可少的.
- 整合PROM促进了以患者为中心的护理策略.
- 进一步的研究可以优化PROM选择和在肝病管理中的应用.
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