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Updated: Jul 8, 2026

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
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使用PacBio长读测序,同时对人类血小板抗原系统和人类白细胞抗原I类位点进行基因定型的新方法

Peizhe Zhao1, Qilu Lyu2, Yi Xu1

  • 1Department of Blood Transfusion, Taiyuan Blood Center, Taiyuan, China.

Vox sanguinis
|October 7, 2024
PubMed
概括

准确的人类白细胞抗原 (HLA) 和人血小板抗原 (HPA) 排型对于血小板输血服务至关重要. 长读测序提供了一种高通量方法来解决HLA和HPA等位基因,有助于建立捐助银行.

关键词:
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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...