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成年人群中视网膜神经纤维层厚度的五年变化:基于人口的队列研究

Hassan Hashemi¹, Mehdi Khabazkhoob², Samira Heydarian³

¹Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.

Clinical & experimental optometry

|October 7, 2024

概括

在健康的成年人中,视网膜神经纤维层 (RNFL) 厚度在五年内保持稳定. 然而,增加的轴长和更的角质测量读数与RNFL稀释有关,较厚的基线测量带来更高的风险.

科学领域:

眼科医生眼科眼科
视网膜成像视网膜成像
纵向研究纵向研究

背景情况:

区分病理性RNFL稀薄与与年龄相关的变化需要了解规范的纵向RNFL厚度.
该研究的重点是45-69岁的个人.

研究的目的:

为了确定健康人群中RNFL厚度的五年变化.
为了识别与随时间变化的RNFL厚度变化相关的因素.

主要方法:

利用了Shahroud眼睛队列研究 (第二和第三阶段) 的数据.
在伊朗,用于参与者招聘的多阶段集群抽样.
收集人口统计数据,视敏度,折射,并利用高清光学连贯断层扫描进行视网膜成像.

主要成果:

平均RNFL厚度显示了0.95±4.15μm的最小五年变化.
RNFL厚度变化与轴长,平均角质测量和基线RNFL厚度相反相关.
超视的个体在平均RNFL厚度上表现出较大的增加,而不是emmetropic个体.
斑点体积与五年平均RNFL厚度的变化直接相关.

结论:

在正常人群中,RNFL厚度变化在五年内在临床上无关紧要.
增加的轴长和更的角质测量读数与RNFL稀释有关.
较高的基线RNFL厚度与随时间变薄的风险更大有关.

关键词:

群组研究是一项群组研究.玻璃眼 glaucoma 玻璃眼玻璃眼玻璃眼玻璃眼眼部生物识别仪器视网膜神经纤维层厚度视网膜神经纤维层厚度

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