KISS1淘汰赛猪的发育特点是低性性性性,正常生长和减少体†
Daniel F Ahern1, Kyra Martins2, Julio M Flórez2,3
1Department of Animal Science, University of Nebraska-Lincoln, Lincoln, NE 68583-0908, USA.
Biology of reproduction
|October 7, 2024
概括
敲除猪中的KISS1基因会导致低阴性性阴性症,减少生殖发育和猪化合物,而不会影响生长. 一个功能性的KISS1等位基因对正常发育来说是足够的.
科学领域:
- 动物科学动物科学
- 生殖生物学 生殖生物学
- 遗传学 遗传学是一种遗传学.
背景情况:
- 基斯佩丁是猪体内淋巴激素分泌的关键调节剂.
- 使用CRISPR/Cas9技术创建了KISS1淘汰的马赛克家长猪系.
- 目的是评估KISS1损失对后代生长和繁殖的影响.
研究的目的:
- 描述具有不同KISS1基因状态 (KISS1+/+,KISS1+/-,KISS1-/-) 的F1猪的生长和生殖发育.
- 评估KISS1淘汰对荷尔蒙水平,生殖腺发育和野猪污染指标的影响.
主要方法:
- 测量体重,性腺激素和的度在野猪和.
- 生殖腺组织的总形态和组织学分析.
- 在野猪脂肪组织中分析skatole和androstenone.
主要成果:
- 在基因型之间没有观察到体重的显著差异.
- 与KISS1+/+和KISS1+/-猪相比,KISS1-/-猪表现出较低的淋巴激素度和阴性淋巴症.
- 在KISS1-/-猪体内,丸激素,皮和罗的水平较低,这表明猪体污染减少了.
结论:
- 完全的KISS1淘汰导致猪的阴阳性性阴阳性症,但不会影响生长.
- 一个单一的功能性KISS1等位基因足以维持正常的淋巴激素分泌和淋巴腺发育.
- 缺少KISS1会减少与野猪污染相关的化合物.
关键词:
发展发展发展发展发展.卵泡刺激激素激素激发卵泡激发激素的激素.亲吻peptin 的时间淘汰赛 淘汰赛 是一个淘汰赛.黄蛋白化激素 (luteinizing hormone) 是一种具有性作用的激素.生殖生殖的繁殖.斯卡托尔斯卡托尔斯 斯卡托尔斯猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪猪测试剂 测试剂 测试剂 测试剂更多相关视频
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