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Updated: Jun 11, 2025

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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Published on: July 21, 2018

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HKDC1作为葡萄糖传感器,通过与PHB2相互作用,促进新陈代谢适应和癌症生长

Panpan Liu1,2, Yao Luo3, Hongyu Wu3,4

  • 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China. liupp@sysucc.org.cn.

Cell death and differentiation
|October 7, 2024
PubMed
概括

基酶DC1 (HKDC1) 感知瘤中的葡萄糖,改变其稳定性以适应新陈代谢. 这种蛋白质通过抑制PHB2促进癌症生长,使HKDC1成为潜在的治疗点.

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