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Updated: Jun 11, 2025

Mouse Fetal Whole Intestine Culture System for Ex Vivo Manipulation of Signaling Pathways and Three-dimensional Live Imaging of Villus Development
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波动力学在胚胎小鼠肠介质中:对光滑肌肉分化的影响

Nicolas R Chevalier1, Léna Zig2, Anthony Gomis2

  • 1Laboratoire Matière et Systèmes Complexes, Université Paris Cité, CNRS UMR 7057, 10 rue Alice Domon et Léonie Duquet, 75013, Paris, France. nicolas.chevalier@u-paris.fr.

Communications biology
|October 7, 2024
PubMed
概括

(Ca2+) 波对于肠道光滑肌肉发育至关重要. 这些波随着平滑肌肉分化而出现,对于肠道延长和细胞存活至关重要,干扰会影响细胞命运.

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Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
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