基于CTA成像特征的Nomogram预测模型的价值评估,用于选择孤立的上层中枢动脉剖析的治疗方法
Xiaodong Jiang1, Dongjian Chen1, Qingbin Meng1
1Department of Interventional Radiology, Second Affiliated Hospital of Nantong University, No.666 Shengli Road, Nantong, Jiangsu, 226014, Jiangsu, China.
BMC medical imaging
|October 7, 2024
概括
一个新的Nomogram模型有效地预测了孤立的上层中枢动脉剖析 (ISMAD) 中保守治疗失败. 关键的风险因素包括低的真光残留比率,长的剖析长度和大动脉角度.
科学领域:
- 血管外科 血管外科
- 放射学 放射学是一门学科.
- 预测建模预测建模
背景情况:
- 隔离上层中枢动脉剖析 (ISMAD) 是一种罕见的疾病,需要仔细选择治疗方法.
- 预测保守治疗失败对于最佳的患者管理至关重要.
研究的目的:
- 开发和验证Nomogram预测模型,使用CTA成像功能来选择ISMAD患者的治疗方法.
- 在ISMAD中确定与保守治疗失败相关的独立风险因素.
主要方法:
- 使用了具有症状的ISMAD患者的培训组 (70%) 和验证组 (30%).
- 分析了保守治疗失败的风险因素,以构建Nomogram预测模型.
- 该模型的预测值使用ROC,Hosmer-Lemeshow和DCA进行了评估.
主要成果:
- 较低的真残留比率 (TLRR),较长的剖析长度和较大的SMA/AA角度被确定为保守治疗失败的高风险因素.
- 在Nomogram模型中,训练组中的AUC为0.826的AUC显示出良好的歧视.
- 该模型在训练和验证组中显示出良好的一致性和临床有效性.
结论:
- 较低的TLRR,较长的剖析长度和较大的SMA/AA角度是ISMAD中保守治疗失败的重要预测因素.
- 开发的Nomogram模型在临床上有效预测ISMAD治疗结果.
相关概念视频
01:28Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...