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皮罗尼斯病低强度体外冲击波治疗:系统性审查和元分析

Guizhong Li¹, Xiao Xu², Libo Man²

¹Department of Urology, Beijing Jishuitan Hospital, Capital Medical University, Xinjiekou East Street, West District, Beijing, 100035, China. lee_gz99@163.com.

|October 7, 2024

概括

低强度的体外冲击波疗法 (LI-ESWT) 在减少皮罗尼病 (PD) 斑块大小和改善阴茎曲和疼痛方面表现有前途. 然而,在审查的研究中,它没有显著改善性功能.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
安德罗学与人类学
再生医学是一种再生医学.

背景情况:

皮罗尼氏病 (PD) 是一种由阴茎曲和斑块形成的疾病.
低强度体外冲击波疗法 (LI-ESWT) 正在作为PD的非侵入性治疗选择进行研究.

研究的目的:

系统地审查和评估LI-ESWT在被诊断为佩罗尼病 (PD) 的患者的疗效.
评估LI-ESWT对PD关键指标的影响,包括斑块大小,曲率,疼痛和性功能.

主要方法:

在Cochrane Registry,PubMed和Embase数据库中进行了系统的文献搜索.
包括包括在2023年2月之前发表的受控试验 (RCT,队列,病例控制) 的研究.
使用斑块大小,曲率偏差,VAS疼痛得分和IIEF来评估治疗的有效性.

主要成果:

分析了7项涉及475名患者的研究.
LI-ESWT显著降低了阴茎斑块大小 (RD 0.27,P=0.02),改善了阴茎曲率 (RD 0.13,P=0.05),并缓解了疼痛 (RD 0.22,P=0.04).
在显著比例的患者中观察到完全缓解 (RD 0.38,P<0.00001),但性功能没有显著改善 (MD 1.44,P=0.53).

结论:

在患有PD的男性中,LI-ESWT显示出降低斑块大小和改善阴茎曲和疼痛的潜力.
建议进一步进行高质量,长期,多中心的随机对照试验,以巩固这些发现并指导临床应用.

关键词:

有控制的试验试验.勃起是一个勃起的过程.进行元分析分析.阴茎的偏差阴茎的偏差皮罗尼氏病是皮罗尼氏病的一种疾病.斑块斑块斑块斑块斑块斑块冲击波是一种冲击波.

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