桃体切除样本的常规组织病理学,这是必要的吗? 一个前性的观察研究
Vidula Mestry1, Ravindra B Sardesai2, Sanjaykumar Sonawale3
1Division of Head and Neck Surgery, Department of Surgical Oncology, Tata Memorial Centre, ACTREC, Mumbai, India.
概括
建议对桃体切除样本进行常规的组织病理学检查. 在8.10%的病例中发现了包括恶性瘤在内的异常发现,需要进一步调查和治疗.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病理学 病理学 病理学
- 手术瘤学手术瘤学
背景情况:
- 由于成本和资源的限制,桃体切除标本的常规组织病理学不是标准实践.
- 桃体切除术通常用于慢性桃体炎,但其他潜在病理可能会在没有检查的情况下错过.
研究的目的:
- 为了评估桃体切除样本中异常组织病理的患病率.
- 确定为桃体切除样本进行例行病原体学的必要性和潜在益处.
主要方法:
- 一项前性观察性研究,涉及111名患者和222名桃体切除标本.
- 对样本进行了基因病理学发现的分析,记录了异常结果并与临床因素相关联.
主要成果:
- 在8.10%的患者中发现了异常组织病理,包括慢性粒瘤,非霍奇金淋巴瘤,早期状细胞癌和胆囊瘤.
- 慢性桃体炎是最常见的发现 (91.89%).
- 桃体不对称,最近出现的症状和年龄较大与异常发现和恶性瘤有显著的相关性.
结论:
- 建议对桃体切除样本进行常规组织病理学检查,以检测需要额外治疗的重大发现.
- 在存在成本限制的情况下,可以采用基于风险的方法,考虑年龄和桃体不对称等因素.
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