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局部抗生素诱导的小肠炎 - - 对病因学和危险因素的系统审查

Maria Pereira¹, Karthik Rao², Florida Sharin¹

¹University Hospital of Leicester, Leicester, UK.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

|October 8, 2024

概括

带有或没有类固醇的局部抗生素是最常见的诱导因子,导致耳炎,一种真菌耳部感染. 建议在处方耳药时谨慎使用,在轻度病例中建议使用乙酸等替代品.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
菌类学菌类学是指菌类学.
传染性疾病传染性疾病

背景情况:

耳菌,外耳的真菌感染,占全球耳部感染的5-20%.
虽然局部和环境因素都涉及到,但它们与自菌病的具体关联需要进一步澄清.

研究的目的:

系统地审查和分析导致自菌病的常见易感因素.
为了确定各种已识别的风险因素的关联强度.

主要方法:

在MEDLINE,EMBASE,CINAHL,ISRCTN和Cochrane数据库中进行了全面的文献搜索.
包括了研究 ototopical 抗生素 (有或没有类固醇) 和其他易感因素的人类研究.
随机效应建模被用于计算 95% 置信区间 (CI) 的聚合流行率估计.

主要成果:

发现的最常见的诱导因素是使用带有或没有类固醇滴的肌肉类抗生素 (47%,95%CI:0.380.56).
其他显著的诱导因素包括使用油和溶剂 (38%,95% CI:0.260.51) 和外听道 (EAC) 的创伤 (37%,95% CI:0.210.54).
阿斯伯吉勒斯菌种是最常见的分离真菌种,大多数研究来自热带和亚热带地区.

结论:

临床医生在为耳部感染处方 ototopical 滴剂时应谨慎使用,因为它们与耳膜炎有很强的关联.
在可行的情况下,应考虑替代性治疗,例如2%的酸,用于轻度的奥托米科斯病例.

关键词:

亚斯珀吉洛斯 (Aspergillus) 是一种植物.这是一种Candida Candida.这种病名为otomycosis.异位类药物异位类药物异位类药物预测因素预测因素

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