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Updated: Jun 11, 2025

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Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
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全喉切除术后法林戈皮的发生率和管理 - - 一个单一的机构10年经验
Subbiah Shanmugam1, S Arunvictor Jebasingh1, S Nagarajan1
1Department of Surgical Oncology, Centre for Oncology, Kilpauk Medical College, MCH Resident, Government Royapettah Hospital, Chennai, India.
概括
喉腔切除术后的皮质神经 (PCF) 与晚期和低白蛋白有关. 虽然保守的管理往往是成功的,救援喉切除术患者可能需要PCF的手术.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 鼻腔皮 (PCF) 是喉腔切除术后的一个常见的术后并发症.
- 鉴定患有PCF高风险的患者仍然具有挑战性,影响治疗时间表和患者的结果.
- 器官保存疗法的兴起增加了喉切除术后PCF的发生率,需要改进管理策略.
研究的目的:
- 研究经过全喉切除术的患者中喉皮质的发生率,诱导因素,管理策略和结果.
- 确定与PCF发育相关的关键风险因素,无论是在前期还是救援喉切除术的情况下.
- 根据患者子组,比较PCF保守与外科治疗的有效性.
主要方法:
- 对72名在2013年至2022年期间接受了全喉切除术的患者的医疗记录进行了回顾性审查.
- 收集的数据包括患者人口统计,瘤特征,手术前治疗 (放射治疗,化疗),营养状况 (白蛋白水平),以及PCF发生和管理的细节.
- 进行了单变异性分析,以确定PCF发展的重大风险因素,并比较前期和救援喉切除组之间的结果.
主要成果:
- 观察到23%的喉皮 (PCF) 的总体发病率,前期喉切除术患者的发病率为16%,救援喉切除术患者的发病率为32%.
- 低的手术前白蛋白水平和晚期瘤阶段 (T阶段) 被确定为PCF的显著风险因素.
- 大多数PCF病例 (64%) 被保守地管理,尽管救援喉切除术患者更可能需要手术干预. PCF患者的平均住院时间为35.6天,比非PCF患者的平均住院时间长得多.
结论:
- 鼻腔皮 (PCF) 是喉切除术的重要并发症,特别是在晚期疾病和低albuminemia的患者中.
- 与前期喉切除术相比,救助喉切除术患者的发病率更高,并且可能需要更大的PCF手术治疗.
- 虽然PCF可以发生在照射和非照射患者中,但积极的营养支持对恢复至关重要.
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