益生菌与益生菌的对比 避孕药:在早产婴儿中预防死角性肠球炎
Sami Ullah1, Inayatullah Khan1, Ayesha Lnu2
1Pediatric Medicine, Lady Reading Hospital Medical Teaching Institute, Peshawar, PAK.
Cureus
|October 8, 2024
概括
益生菌显著降低了早产婴儿死性肠球炎 (NEC) 的发生率. 这种干预措施还降低了败血症率,缩短了住院时间,改善了体重增加,支持其在新生儿护理中的使用.
科学领域:
- 新生儿医学 新生儿医学
- 胃肠病学 胃肠病学
- 微生物学 微生物学
背景情况:
- 结核性肠球炎 (NEC) 是早产婴儿的关键性胃肠道疾病,与高发病率和死亡率有关.
- 对NEC有效的预防策略对于改善脆弱新生儿的结果至关重要.
研究的目的:
- 评估益生菌补充剂在预防早产婴儿中NEC的有效性.
- 评估益生菌对死亡率,晚发性败血症,住院时间和婴儿体重增加的影响.
主要方法:
- 进行了一项前性队列研究,涉及102名早产婴儿.
- 参与者每天接受口服益生菌 (Lactobacillus和Bifidobacterium物种) 或安慰剂.
- 随机分配确保了两组之间的公正比较.
主要成果:
- 益生菌的使用显著降低了NEC发病率 (7.8%与21.6%,p=0.04).
- 益生菌组经历了晚发性败血症的减少 (13.7%与29.4%,p=0.03),住院时间更短 (42.5与48.1天,p=0.02),体重增加增加 (15.3与13.4克/天,p=0.01).
结论:
- 益生菌在预防早产婴儿的NEC和相关并发症方面具有显著的益处.
- 研究结果支持在新生儿重症监护中常规使用益生菌,特别是在资源有限的环境中.
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