在癌症诊断和死亡风险之前和之后的身体活动在三个大型前性队列中
Cami N Christopher1,2,3, Paulette D Chandler4,5, Xuehong Zhang4,6,7,8
1Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. cchristopher@fas.harvard.edu.
Cancer causes & control : CCC
|October 8, 2024
概括
在癌症诊断之前和之后保持体力活动 (PA) 可以显著降低死亡风险. 诊断后变得活跃也改善了生存率,突出了癌症患者运动的重要性.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 身体活动 (PA) 与改善癌症存活率有关.
- 在癌症患者的死亡风险上PA的时间的影响仍然不清楚.
研究的目的:
- 评估癌症诊断前后身体活动水平与死亡风险之间的关联.
- 分析女性健康研究 (WHS) 和医生健康研究 (PHS) -I和PHS-II队列中的PA时间.
主要方法:
- 参与者根据诊断前和诊断后的PA水平被分类为活跃或不活跃.
- 分析了四个联合的PA类别:不活跃→不活跃,活跃→不活跃,不活跃→活跃和活跃→活跃.
- 使用多变量Cox比例危险回归来评估死亡风险.
主要成果:
- 与保持不活动相比,在诊断前和诊断后保持活跃显示出较低的全因,癌症和非癌症/心血管疾病死亡风险.
- 诊断后变得活跃与减少全因,癌症和非癌症/心血管疾病死亡率有关.
- 在诊断前和诊断后的活动表明死亡风险较低,尽管根据队列和结果的意义不同.
结论:
- 在癌症诊断时保持或采取体育活动可能会改善癌症存活率.
- 需要对不同癌症群体进行进一步的研究来证实这些发现.
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