患有COVID-19和尾炎的儿童的临床结果:倾向性得分匹配分析
Marjorie N Odegard1, Olivia A Keane2, Shadassa A Ourshalimian1
1Division of Pediatric Surgery, Department of Surgery, Keck School of Medicine, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Mailstop #100, Los AngelesLos Angeles, CACA, 90027, USA.
Pediatric surgery international
|October 8, 2024
概括
儿科尾切除术的结果对于患有和没有COVID-19的儿童来说是相似的. 在COVID-19感染的儿童中,尾炎的前置手术显示了与没有病毒的儿童相似的结果.
科学领域:
- 儿科手术 儿科手术
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 早期的COVID-19流行病看到COVID-19的儿科尾炎的非手术管理,随后是间歇性尾切除.
- 目前的做法有利于为患有尾炎和COVID-19的儿童进行前期尾切除.
- 这种转变对患者结果的影响仍然不清楚.
研究的目的:
- 为了比较经过尾切除术的儿科患者的手术结果,按COVID-19状态分层.
- 评估前期尾切除术在患有同时尾炎和COVID-19的儿童中的安全性和有效性.
主要方法:
- 在50家儿童医院进行了回顾性队列研究.
- 包括在2020年3月至2022年7月期间接受尾切除手术的21岁以下儿童.
- 倾向性得分匹配用于比较COVID-19阳性和阴性患者,分析住院时间,排水位,再入院和机械通风.
主要成果:
- 分析了1360名COVID-19阳性和1360名COVID-19阴性儿童的匹配队列.
- 患有COVID-19的儿童住院时间较短 (1天 vs. 2天),术后排水时间较少 (2.4% vs. 4.1%).
- 在COVID-19组中,三十天再入院率较低 (9.0%对11.4%),机械通风要求没有显著差异.
结论:
- 在COVID-19感染的背景下,为儿科尾炎进行前置尾切除术,其结果与没有COVID-19的患者相似.
- 这项研究支持目前的尾炎和COVID-19儿童的手术管理方法.
- 在接受尾切除的COVID-19阳性患者中,没有观察到呼吸器需求的风险增加.
相关概念视频
01:29Appendicitis-II: Diagnostic Studies and Management
66
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
66
01:22Appendicitis-I: Introduction
91
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
91
01:20Comparing the Survival Analysis of Two or More Groups
156
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
156