2011年至2021年亚马逊州马纳乌斯结核病治疗失败的相关因素
Felipe Alves de Almeida1, Maria Jacirema Ferreira Gonçalves2
1Universidade Federal do Amazonas, Escola de Enfermagem de Manaus, Programa de Pós-Graduação em Enfermagem, Manaus, AM, Brazil.
Revista da Escola de Enfermagem da U S P
|October 8, 2024
概括
个人和社会脆弱性显著增加了肺结核治疗结果不成功的风险. 有针对性的干预措施对于解决这些因素和改善患者治疗结果至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 结核病 (TB) 仍然是一个全球性卫生挑战,治疗成功率差异很大.
- 了解脆弱性因素对于制定有效的结核病控制策略至关重要.
研究的目的:
- 确定与结核病治疗结果不成功相关的个人,程序和社会脆弱性因素.
- 为了分析2011年至2021年间亚马逊州马纳乌斯的数据.
主要方法:
- 生态研究利用可通知的疾病信息系统 (2011-2021) 的结核病例通知的数据.
- 分析治疗结果 (死亡,失去了随访,默认) 和患者的脆弱性.
- 逻辑回归使用层次模型来估计赔率比率和置信区间.
主要成果:
- 与不成功治疗相关的个体脆弱性因素包括特定年龄组 (20-29岁,>60岁),土著种族,艾滋病毒同时感染和吸毒.
- 程序的脆弱性与没有进行艾滋病毒检测有关.
- 社会脆弱性与属于特殊人群有关.
结论:
- 个人脆弱性与结核病治疗失败的最强相关性.
- 干预措施应侧重于解决关键的个人弱点,以防止治疗失败.
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