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补充因子H 是一个ICOS连接体,在质瘤微环境中调节Tregs

Karolina I Smolag1, Jakub Olszowka1, Rebecca Rosberg2

  • 1Section of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö, Sweden.

Cancer immunology research
|October 8, 2024
PubMed
概括

补充因子H (FH) 在质瘤中促进调节性T细胞 (Treg) 的存活和功能,导致免疫抑制性瘤微环境和更差的患者预后. 评估FH可以预测免疫疗法反应.

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