双卷积变压器UNet (DCT-UNet) 用于有风险的器官和临床目标体积细分在MRI中用于宫癌支臂疗法
Gayoung Kim1, Akila N Viswanathan1, Rohini Bhatia1
1Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, MD, United States of America.
Physics in medicine and biology
|October 8, 2024
概括
一个新的深度学习模型,DCT-UNet,自动对子宫癌基治疗的风险器官和高风险临床目标体积进行细分. 这种人工智能方法显著减少了轮时间,并与手工方法相比提高了准确性.
科学领域:
- 医疗成像医学成像
- 在瘤学中使用人工智能
- 放射治疗规划 放射治疗规划
背景情况:
- 磁共振成像 (MRI) 是用于宫癌的高剂量支臂治疗的标准.
- 对有风险的器官 (OAR) 和高风险的临床目标体积 (HR-CTV) 的准确细分对于放射治疗规划至关重要.
- 手动轮是耗时的,容易出现不准确的情况.
研究的目的:
- 开发和评估一种深度学习方法,用于从盆腔MRI中自动细分OAR (膀,直肠,直肠) 和HR-CTV.
- 为了克服手动轮的精度和时间的局限性,用于宫癌支臂疗法.
主要方法:
- 一个双卷积变压器UNet (DCT-UNet) 架构被设计为粗细分段.
- 一个两阶段的管道涉及最初的粗多器官细分,随后是器官特定细分.
- 在HR-CTV细分上采用了适应尺寸的多模型策略,以处理可变尺寸.
主要成果:
- 在DCT-UNet中,OAR (膀:0.932,直肠:0.786,直肠:0.663) 和HR-CTV (0.741) 中获得了高的子相似系数.
- 该模型的表现优于其他最先进的细分方法,并且表现得与人类观察者相当.
- 整个细分管道平均在12.59秒内处理每个受试者,比手动轮 (>15分钟) 快得多.
结论:
- 拟议的DCT-UNet模型提供了一个快速而准确的解决方案,用于在宫癌基治疗中自动OAR和HR-CTV细分.
- 这种深度学习方法有可能提高放射治疗计划的一致性和效率.
- 源代码是公开的,这有助于进一步的研究和临床实施.
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