1994年至2019年爱尔兰甲状腺癌流行病学 - 增加诊断但没有死亡率的好处
Gerard P Sexton1, Thomas J Crotty2, Susannah M Staunton3
1Department of Otolaryngology, Head & Neck Surgery, St James's Hospital, Dublin 8, Ireland; Royal College of Surgeons in Ireland, Ireland.
概括
甲状腺癌的发病率,特别是早期的乳头甲状腺癌 (PTC),在爱尔兰显著增加. 包括放射性使用在内的管理策略也发生了转变,反映了全球趋势.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 甲状腺癌的流行病学和管理在全球范围内发生了重大变化.
- 在国际上,乳头甲状腺癌 (PTC) 发病率在早期阶段显著上升.
研究的目的:
- 审查爱尔兰甲状腺癌的流行病学.
- 分析发病率,诊断,治疗和生存率的趋势.
主要方法:
- 使用爱尔兰国家癌症登记处的数据进行了回顾性队列研究.
- 从1994年到2019年,分析了4158名患者的病历.
主要成果:
- 甲状腺癌发病率增加了三倍以上,T1 PTC增加了十二倍.
- 乳头甲状腺癌 (PTC) 是最常见的诊断 (70%),疾病特异性5年生存率 (DSS) 为97%.
- 放射性 (RAI) 的使用显著下降,但在老年PTC患者中改善了DSS.
结论:
- 爱尔兰的甲状腺癌流行病学和管理反映了国际趋势.
- 早期PTC发生率显著增加和治疗方法的变化是显而易见的.
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