在COVID-19和非COVID-19病例之间对后感染性嗅觉功能障碍的比较分析
Tae-Seong Eo1, Yeonsu Jeong1, Hyung-Ju Cho1,2
1Department of Otorhinolaryngology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Scientific reports
|October 8, 2024
概括
与COVID-19相关的嗅觉功能障碍 (OD) 影响年轻男性,并且显示出比非COVID-19 OD更好的初始功能. 在治疗后,COVID-19 OD改善了气味检测,而非COVID-19 OD改善了气味识别.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 神经学 神经学
背景情况:
- 感染后嗅觉功能障碍 (PIOD) 可能与各种病毒感染有关.
- 区分COVID-19相关的和非COVID-19相关的嗅觉功能障碍对于了解疾病特征和治疗结果至关重要.
研究的目的:
- 为了比较COVID-19相关的嗅觉功能障碍 (OD) 与非COVID-19相关的OD患者的人口统计和临床特征.
- 分析两组之间嗅觉功能测试结果和治疗反应的差异.
主要方法:
- 对169名患有PIOD的患者的人口和临床数据的分析.
- 在COVID-19和非COVID-19组之间对嗅觉问卷和嗅觉功能测试结果 (TDI,歧视,识别,值) 的比较.
- 对嗅觉功能障碍治疗结果的评估.
主要成果:
- 与非COVID-19组 (70名患者) 相比,COVID-19组 (99名患者) 较年轻,男性更频繁,并报告了较高的风湿率.
- 最初的嗅觉功能测试显示,COVID-19组的TDI,歧视和识别得分明显更高.
- 在治疗后,COVID-19组的气味检测值有所改善,而非COVID-19组的气味识别有所改善.
结论:
- 与COVID-19相关的OD具有独特的特征,包括年龄较小,男性占主导地位,较高的帕洛斯米亚发病率和较好的初始嗅觉功能,与非COVID-19的OD相比.
- 治疗策略可能需要量身定制,因为在COVID-19相关病例中,气味检测随着治疗而改善,而气味识别在非COVID-19相关病例中显示出改善.
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