在中年和老年人群中,氧化平衡得分和腹腔大动脉化之间存在关联
Zongao Cai1, Jiachen She2, Shuang Guo1
1Department of Vascular Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China.
BMC cardiovascular disorders
|October 8, 2024
概括
更高的氧化平衡评分 (OBS),反映出更好的抗氧化状态,与40岁以上成年人腹腔大动脉化 (AAC) 的较低患病率有关. 这表明OBS可能有助于减少AAC负担.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 衰老研究研究 衰老研究
背景情况:
- 氧化平衡评分 (OBS) 量化了一个人的抗氧化能力.
- 腹腔大动脉化 (AAC) 是心血管疾病的标志物.
- 了解影响AAC的因素对于公共卫生至关重要.
研究的目的:
- 调查氧化平衡评分 (OBS) 和腹腔大动脉化 (AAC) 之间的关联.
- 为了分析40岁及以上的成年人之间的这种关系.
主要方法:
- 一项以人口为基础的横截面研究,利用国家健康和营养检查调查 (NHANES) 数据 (2013-2014).
- 包括2520名40岁及以上的成年人.
- 员工调查加权的多变量物流和受限制的立方螺纹模型来评估OBS-AAC协会.
主要成果:
- 在OBS和AAC患病率 (OR 0.98,95% CI 0.96-1.00) 之间观察到一个显著的反向关联.
- 确定了OBS和AAC之间的非线性剂量反应关系.
- 亚组分析证实,这种反向关系在不同种群中是一致的.
结论:
- 较高的OBS与40岁以上成年人中AAC的患病率相反相关.
- 保持强大的OBS可以在减轻腹腔大动脉化的负担方面发挥保护作用.
- 对抗氧化剂状态和心血管健康的进一步研究是有必要的.
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