基于拓指数的VIKOR辅助多标准决策技术用于肺部疾病
Tahreem Ashraf1, Nazeran Idrees1
1Department of Mathematics, Government College University, Faisalabad, Pakistan.
本研究使用图形理论和VIKOR方法根据其结构和特性对肺部疾病药物进行排名. 这种方法有助于选择有效的治疗方法,以改善患者护理.
科学领域:
- 药用化学 医学化学
- 计算化学的计算化学
- 药理学 药理学是指药理学的学科.
背景情况:
- 全球肺部疾病患病率不断上升,需要新的治疗策略.
- 慢性肺部疾病往往导致药物耐药性和副作用.
- 开发有效的药物组合对于管理肺部疾病至关重要.
研究的目的:
- 用拓指数和基于度的图形不变量来分析肺部疾病药物.
- 为QSPR分析,将药物结构与其物理性质相关联.
- 为了优化药物优先考虑肺部疾病治疗.
主要方法:
- 利用了16种肺部疾病药物的数据集.
- 应用基于度的图形不变量来描述药物结构.
- 使用了VIKOR (VlseKriterijumska Optimizacija I Kompromisno Resenje) 方法来对药物进行排名.
主要成果:
- 建立了药物结构和物理性质之间的相关性.
- 维科尔方法为每个药物提供了最佳的排名.
- QSPR的结果证明了该方法在药物优先级的有效性.
结论:
- 该方法提高了肺部疾病治疗方法的战略选择.
- 为临床决策和药物开发提供了宝贵的见解.
- 旨在改善治疗肺部疾病的患者护理和资源配置.
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