优化纯种选择,以提高杂交品种的表现
Somayeh Barani1, Sayed Reza Miraie Ashtiani1, Ardeshir Nejati Javaremi1
1Department of Animal Science, Faculty of Agriculture, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran.
Frontiers in genetics
|October 9, 2024
概括
使用纯种数据预测杂交的性能 (CP) 是至关重要的. 杂交和纯种种群之间的遗传相关性显著影响预测的准确性,最佳模型取决于这个值和数据整合策略.
科学领域:
- 动物育种和遗传学动物育种和遗传学
- 定量遗传学 是一种定量遗传学.
- 畜牧业生产 畜牧业生产
背景情况:
- 杂交通过异构和品种互补性来提高牲畜生产.
- 预测杂交表现 (CP) 往往依赖于纯种数据,因为杂交记录的稀缺性.
- 准确的CP预测需要考虑非添加性遗传效应和环境因素,这些因素受到种群之间的遗传相关性 () 的影响.
研究的目的:
- 调查整合纯种和杂交数据的战略,以实现最佳的CP预测.
- 在不同基因相关性水平下评估单步基因组最佳线性无偏预测 (ssGBLUP) 和带有元发现者 (ssGBLUP-MF) 的ssGBLUP模型.
- 确定最有效的模型,在不同的场景中最大限度地提高CP.
主要方法:
- 使用了一种双向杂交模拟.
- 场景探索了来自纯种和杂交种群的基因型个体.
- ssGBLUP和ssGBLUP-MF模型与BLUP与未知母组 (BLUP-UPG) 相比较.
主要成果:
- 在所有场景中,预测准确性随着值的增加而增加.
- 在将母品种和杂交品种的基因型结合起来时,ssGBLUP和ssGBLUP-MF的准确性相似,最高值为<0.5.5.
- 在 = 0.8 时,ssGBLUP 仅使用 sire 品种基因型实现了最高的准确性 (73.2%).
- BLUP-UPG 始终显示的精度低于 ssGBLUP 和 ssGBLUP-MF.
- 结合杂交和纯种基因型,在较低的基因水平上改善了预测,而在较高的基因水平上,父亲基因型优越.
结论:
- 基因相关性 () 是从纯种数据预测CP的关键因素.
- 对CP的最佳预测模型取决于影响
- 需要进一步的研究来开发能够优化纯种选以提高CP的模型.
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