检查与双极性障碍青年药物坚持相关的检查因素
Mohamed Y Elhosary1, John A Merranko1, Tina R Goldstein1
1UPMC Western Psychiatric Hospital, University of Pittsburgh, Pittsburgh, Pennsylvania.
JAACAP open
|October 9, 2024
概括
在患有双相情感障碍 (BD) 的年轻人中,缺乏药物坚持是常见的,并发性ADHD是主要因素. 解决ADHD和患者关注的问题是改善治疗结果的关键.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
背景情况:
- 药物坚持对于管理青年双相情感障碍 (BD) 至关重要.
- 这种人群中对坚持挑战的纵向数据是有限的.
研究的目的:
- 评估从青春期到年轻成年期患有BD的年轻人对药物的坚持.
- 识别与不良药物坚持相关的因素.
主要方法:
- 从双极性青年 (COBY) 的过程和结果研究中对179名参与者 (12-36岁) 的纵向分析.
- 药物坚持度在平均8年内使用验证的问卷进行评估.
- 使用单变量和多变量模型分析的非坚持的同时和未来预测因素.
主要成果:
- 在超过50%的随访中,51%的参与者报告了不良的坚持.
- 伴随性ADHD是所有年龄组不良执法最强的预测因素.
- 报告中最常见的不遵守的原因包括遗忘,负面态度和破坏日常生活.
结论:
- 药物不够坚持是患有BD的年轻人的一个重要问题,与并发性ADHD密切相关.
- 治疗并发性ADHD对于改善坚持和预后至关重要.
- 干预措施应解决患者的担忧,并支持持续服用药物.
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