用于与食品接触的产品中的潜在乳腺致癌物:对政策,执法和预防的影响
Lindsey V Parkinson1, Birgit Geueke1, Jane Muncke1
1Food Packaging Forum Foundation, Zürich, Switzerland.
Frontiers in toxicology
|October 9, 2024
概括
许多潜在的乳腺致癌物从与食品接触材料 (FCM) 迁移,造成广泛的公共卫生风险. 减少暴露需要更新评估和管理与食品接触化学品的政策.
科学领域:
- 环境健康 环境健康
- 毒理学 毒理学 毒理学
- 食品安全 食品安全
背景情况:
- 食品接触材料 (FCM) 立法旨在保护公众健康免受危险化学品,包括基因毒性致癌物质的影响.
- 尽管有规定,但乳腺癌等癌症仍然普遍存在,这表明化学品安全评估中存在潜在的差距.
- 毒性物质的关键特征框架确定了921种潜在的乳腺致癌物质.
研究的目的:
- 评估与食品接触材料中的潜在乳腺致癌物质的流行程度.
- 通过FCM确定人类接触这些化学品的程度.
- 通过政策变化突出公共卫生干预的机会.
主要方法:
- 对比了921种潜在的乳腺致癌物质 (由Kay等人确定) 的列表. 与迁移和可提取的接触食品化学品 (FCCmigex) 数据库.
- 分析了2020-2022年间发布的全球FCM的迁移研究.
- 专注于在实际使用条件下迁移的化学品.
主要成果:
- 189 (21%) 的潜在乳腺致癌物已在FCM中检测到.
- 在最近的研究 (2020-2022) 中,发现76种潜在的乳腺致癌物从全球销售的FCM迁移.
- 这表明人口广泛,长期暴露于这些化学物质.
结论:
- 由于许多潜在的乳腺致癌物的迁移,目前的FCM存在重大风险.
- 从FCM中暴露于这些化学物质的全人口暴露是一个常见的现象.
- 以科学为基础的政策修正对于改善食品接触化学品的评估和管理至关重要,以减少癌症风险.
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