在大脑麻的成年人中淋巴的发生率
Christine R Gettys1, Sean Smith1, Kimberly K Rauch2
1Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, Michigan, USA.
PM & R : the journal of injury, function, and rehabilitation
|October 9, 2024
概括
患有脑性麻 (CP) 的成年人患淋巴结胀的风险明显更高. 这项研究发现,与患有CP的女性相比,患有CP的男性患病率不成比例地高.
科学领域:
- 医学研究 医学研究
- 临床流行病学临床流行病学
- 公共卫生 公共卫生
背景情况:
- 淋巴水是一种慢性疾病,在患有脑 (CP) 的成年人中经常被研究不足.
- 了解CP的淋巴 edem 发病率对于患者护理和资源分配至关重要.
研究的目的:
- 为了比较CP和没有CP的成年人中淋巴的2年发病率.
- 在调整多病症,癌症和淋巴结手术后分析这种发病率.
主要方法:
- 使用全国商业索赔数据 (2011-2017年) 的回顾性队列研究.
- 包括18岁以上有/没有CP的成年人,分析了12个月的共同疾病 (惠特尼共同疾病指数 - WCI),癌症和之前的淋巴结手术的基线数据.
- 评估了2年淋巴发病率 (IR) 并使用考克斯回归来估计根据关键因素调整的危险比率 (HR).
主要成果:
- 在患有CP的成年人中,2年淋巴发病率为5.73%,在没有CP的成年人中为1.81 (IRR=3.17).
- 在患有CP的成年人中,淋巴的调整后危险比为2.43.
- 根据性别,年龄和WCI观察到效果修饰;患有CP的男性和患有CP的年轻人表现出较高的相对风险.
结论:
- 患有脑的成年人面临患有淋巴的风险要大得多.
- 与CP的男性相比,与CP的女性相比,患有CP的男性在淋巴结胀率上呈现出不成比例的增加,相对于他们各自的无CP对照组.
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