与客观和主观认知相关的可修改的痴呆风险因素
Anna Marie Rosická1, Vanessa Teckentrup1, Sol Fittipaldi1,2,3
1School of Psychology, Trinity College Dublin, Dublin, Ireland.
概括
主观认知投诉与客观措施不同,与生活方式和健康状况等痴呆症风险因素密切相关. 智能手机评估显示,对所有年龄段的认知变化进行早期检测是有希望的.
科学领域:
- 认知科学是一种认知科学.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 早期发现主观和客观认知障碍对于及时干预至关重要.
- 在健康个体中,主观认知投诉可能会先于客观认知缺陷.
- 可修改的痴呆风险因素与不同类型的认知障碍之间的关系需要进一步澄清.
研究的目的:
- 调查13个可修改的痴呆风险因素与主观记忆抱怨和执行功能的客观测量之间的联系.
- 为了确定主观认知是否比客观认知更敏感于痴呆风险因素.
- 探索智能手机应用程序在早期认知障碍检测方面的潜力.
主要方法:
- 通过智能手机应用程序招募了大量的横截面样本 (N=3327,年龄18-84岁).
- 研究人员量化了13个风险因素与主观记忆之间的关联.
- 评估了风险因素与三个客观执行功能指标 (视觉工作记忆,认知灵活性,基于模型的规划) 之间的关联.
主要成果:
- 包括抑郁症,社会经济地位,听力障碍,孤独,教育,吸烟,耳,运动水平,社交网络规模,中风,糖尿病和高血压在内的众多因素与认知障碍有关.
- 主观记忆问题与大多数风险因素的关联最强,即使考虑到抑郁症.
- 这些关联在整个生命周期中通常是一致的,并没有因年龄而显著减弱.
结论:
- 与客观认知措施相比,主观认知评估似乎对自我报告的痴呆风险因素更敏感.
- 基于智能手机的认知评估表明对各种痴呆症风险因素的敏感性.
- 这些发现表明,移动健康技术可以在早期识别认知衰退方面发挥重要作用.
关键词:
年龄的相互作用.认知灵活性 认知灵活性认知障碍是一种认知障碍.一个横截面研究.抑郁 抑郁症 抑郁症 抑郁症 是一种执行职能 执行职能是指执行职能.基于模型的规划计划.痴呆症的可改变的风险因素智能手机评估 智能手机评估智能手机数据收集数据收集主观认知投诉的主观认知投诉主观记忆问题 主观记忆问题视觉工作记忆 视觉工作记忆更多相关视频
相关概念视频
01:30Dementia
97
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
97
01:30Cognitive Development During Adulthood
65
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
65
01:26Alzheimer's Disease: Overview
449
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
449
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
106
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
106
01:22Alzheimer's Disease: Treatment
166
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
166
01:26Aging
37
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
37