患有孤立胸部创伤的患者的预后指标:一个回顾性横截面研究
Ramiz Yazıcı1, Bensu Bulut2, Murat Genc3
1Department of Emergency Medicine, University of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul-Türkiye.
概括
较高的冲击指数 (SI),葡萄糖/比和乳酸水平预测了孤立的胸部创伤患者的死亡率. 这些关键指标可以帮助临床决策,并改善创伤幸存者的结果.
科学领域:
- 创伤外科 手术 创伤外科
- 紧急医疗 紧急医疗
- 临床生物化学 临床生物化学
背景情况:
- 胸部创伤是导致死亡的主要原因,特别是在急诊室的到来.
- 确定可靠的预后标志物对于管理孤立胸部创伤患者至关重要.
研究的目的:
- 为了研究死亡率和冲击指数 (SI) 与特定的代谢和生化标志物之间的关联,在患有孤立胸部创伤的患者中.
- 评估SI和生物标志物的预测能力,以估计死亡率.
主要方法:
- 针对患有孤立胸部创伤的成年患者进行了回顾性横截面研究 (2019年1月 - 2023年12月).
- 在入院时分析冲击指数 (SI) 和选定的生物标志物.
- 用于确定预测能力 (AUC) 的接收器操作特征 (ROC) 曲线.
- 使用尤登指数方法识别的最佳切割值.
主要成果:
- 该研究包括352名患者;死亡率为9.6%.
- 较高的冲击指数 (SI) (AUC=0.885),葡萄糖/比 (AUC=0.869) 和乳酸水平 (AUC=0.832) 与增加的死亡率有显著联系.
- 为SI (1.02),葡萄糖/比率 (36.85),电离 (1.23) 和乳酸盐 (1.98) 确定了最佳切割值.
结论:
- 较高的冲击指数 (SI),葡萄糖/比和乳酸水平是孤立胸部创伤中死亡率的重要预测因素.
- 这些标志物作为有效的预后指标.
- 这些发现可以指导临床决策,以潜在地改善胸部创伤患者的治疗结果.
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