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Updated: Jun 11, 2025

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
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Published on: October 2, 2018

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在脏疾病中受损的11β-Hydroxysteroid脱酶2型活性 破坏了11-氧化生物合成

Maria Tomkins1,2, Tara McDonnell1,2, Leanne Cussen1,2

  • 1Androgens in Health and Disease Research Group, Academic Division of Endocrinology, Department of Medicine, Royal College of Surgeons in Ireland, Dublin, D09 V2N0, Ireland.

The Journal of clinical endocrinology and metabolism
|October 9, 2024
PubMed
概括

慢性病损害了11-oxygenated androgen生物合成,这是由于中的11β-hydroxysteroid脱酶2型 (HSD11B2) 酶的活性降低. 这项研究证实了HSD11B2的存在.

关键词:
含有11氧的原体.11β-基类固醇脱酶2型2β-基类固醇脱酶2型慢性脏疾病 慢性脏疾病类固醇的生物合成.

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